Star Rating

"This is the first probiotic that I’ve ever felt. It really helps with hunger after meals and sugar cravings! I’II definitely be buying again."

- Paula S., Verified Customer

Our patented probiotic formula converts excess sugars (glucose & fructose) into mannitol, a free radical scavenger that is naturally eliminated. Experience a positive metabolic shift. You’ll love the way a balanced gut microbiome makes you feel. Go ahead, make the shift.

4.1
Rated 4.1 out of 5 stars
485 Reviews

50,000+ happy customers

Sugar Shift®

Sugar Shift®

Shift your sugar metabolism and
start your journey to better health.

Experience the whole body benefits of our patented probiotic Sugar Shift®

  • Improves bowel regularity. Provides relief of both diarrhea and constipation.
  • Restores overall digestive health to make you feel better.
  • Decreases sugar and carb cravings over time.
  • Boosts energy and lessens fatigue keeping you active and refreshed.
  • Improves glucose metabolism by reducing levels of blood glucose.
Regular price $49.99
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All BiotiQuest® products are:

Gluten-free

Dairy-free

Soy-free

Non-GMO

Vegan

How Sugar Shift® Works

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The Sugar Shift® team of carefully selected bacterial strains works together in harmony to transform excess sugars—such as glucose and fructose—into mannitol, a powerful free radical scavenger with unique health benefits. This natural conversion reduces the burden of sugar spikes in the bloodstream while simultaneously producing mannitol, which acts as a prebiotic to feed beneficial microbes and promote a more diverse, resilient microbiome.

Mannitol is not metabolized by your body in the same way as glucose or fructose. Instead, it nourishes gut health before being safely excreted in the urine. This dual-action process supports healthier sugar metabolism and contributes to overall gut health, making Sugar Shift® a truly innovative approach to managing the modern challenges of sugar-heavy diets.

What sets Sugar Shift® apart is its targeted team of probiotic strains—a thoughtfully assembled guild designed to restore balance within the microbiome. It’s not just another probiotic; it’s the first of its kind, a focused, natural solution for supporting your metabolic and gut health.

We created Sugar Shift® to help my husband, John, after his Parkinson’s diagnosis. Through my research, I discovered how deeply sugar—especially fructose—disrupts the microbiome and drives metabolic imbalance. Hidden in so many foods, these sugars are nearly impossible to avoid, yet they take a toll on overall health.

Sugar Shift® is more than just a probiotic—it’s a breakthrough in gut and metabolic health. While many probiotics focus solely on adding “good” bacteria to the gut, Sugar Shift® introduces a targeted team of bacteria that actively work to transform health at its root.

This multi-strain formulation not only converts excess sugars—like glucose and fructose—into beneficial compounds such as mannitol, but also:

  • Supports detoxification by breaking down environmental toxins like glyphosate.
  • Boosts short-chain fatty acids like butyrate, which nourish and protect the cells lining your gut.
  • Shifts the microbiome away from producing inflammatory endotoxins, promoting a healthier and more balanced ecosystem.

By restoring microbiome balance and diversity, Sugar Shift® helps support nutrient absorption, detoxification, reduced inflammation, and sustained energy. It’s not just about managing sugar—it’s about transforming the way your body thrives in today’s challenging environment.

Take 2 capsules per day. We recommend taking 1 in the morning and 1 around dinner time.

Lactobacillus plantarum (TBC LP-36™):

  • Breaks down acetaldehyde, which can harm membranes, and produces butyrate to protect the gut barrier.
  • Effectively controls pathogens by generating potent antimicrobial peptides.
  • Unique ability to degrade glyphosate and remove heavy metals like aluminum.

Leuconostoc mesenteroides (TBC LM-37™):

  • Converts glucose and fructose into mannitol, a potent free radical scavenger.
  • Produces anti-inflammatory compounds, safeguards the gut lining, and synthesizes vitamin B12.

Pediococcus acidilactici (TBC PA-68™):

  • Primarily controls pathogens by producing the bacteriocin pediocin A, known for its antiviral and anti-listerial properties.
  • May prevent inflammatory compounds from crossing the gut lining.

Lactobacillus paracasei:

  • Breaks down proteins while increasing amino acid absorption.
  • Has Immune boosting and anti-inflammatory characteristics.

Bacillus subtilis (DE111® by Deerland)

  • Enhances immune function and pathogen control.
  • Regulates gastrointestinal health, aiding with diarrhea and constipation.
  • Increases muscle mass and reduces body fat.

Bifidobacterium bifidum:

  • Interacts with the immune system, facilitating communication with immune cells in the gut's mucosal lining.
  • Stimulates the growth of commensal bacteria that produce butyrate to support gut lining health.

Bifidobacterium longum:

  • Offers protection against pathogens and modulates the immune system.
  • Provides essential nutrients by digesting resistant carbohydrates.
  • May alleviate the effects of acute stress, reducing oxidative stress and stimulating sleep centers in the brain.

Lactobacillus reuteri (PCR07):

  • Produces antimicrobial substances and converts glucose to mannitol.
  • May reduce the production of pro-inflammatory cytokines.
  • Associated with increased oxytocin production and accelerated wound healing.

We believe in the transformative potential of Sugar Shift® and want you to feel confident in giving it a try. That’s why we offer a satisfaction guarantee. If you’re not completely satisfied with how you feel after using our product, simply contact us within 30 days of your purchase, and we’ll refund your full purchase price.

This is our way of supporting your health journey—so you can take this important step toward better wellness with confidence.

4.1
Rated 4.1 out of 5 stars
Based on 485 reviews
Total 5 star reviews: 306 Total 4 star reviews: 56 Total 3 star reviews: 53 Total 2 star reviews: 27 Total 1 star reviews: 43
75%would recommend this product
485 reviews
  • YW
    Yvonne W.
    Flag of United States
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago
    Hubby lost 10 pounds without any diet change

    I found out about Sugar Shift from Dr. William Davis, as I am following his program. I’ve been making Sugar Shift into a yogurt for myself (I love it!)… but the big story is my hubby. I finally got him to start taking supplements maybe 6 months ago. Then a couple months ago, I begin sneaking Sugar Shift Capsules in there, 2 per day; he did not know. Over the past 2 months, he has lost over 10 pounds! First he said, his pants were too loose. He was really excited. He lost weight without trying at all, no change in diet. I finally had to confess about the Sugar Shift ha ha! We are pretty sure it HAS to be the Sugar Shift! He is now inspired to try eating better, as well! Thank you!

  • BH
    Barbara H.
    Flag of United States
    Verified Buyer
    Rated 3 out of 5 stars
    3 months ago
    Shift?

    Not sure it’s had an effect.

    BiotiQuest
    2 months ago

    Hi Barbara,

    Thank you for taking the time to leave a review. I appreciate your honesty and that you’re giving the products a real try.

    When someone says they’re not sure if Sugar Shift is having an effect, it’s often helpful to take a closer look at what specific changes they were hoping to see. If you’re open to sharing more about your goals or what led you to try these formulas, we’d be happy to offer more tailored guidance.

    Every microbiome is different, and sometimes small adjustments in timing, combinations, or expectations can make a real difference.

    Feel free to reply here or reach out directly at info@biotiquest.com.

    With Gratitude,
    Jack
    BiotiQuest Probiotics

  • JM
    Jameela M.
    Flag of United States
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    3 months ago
    Great so far!

    I like the product.

  • JM
    James M.
    Flag of United States
    I recommend this product
    Rated 5 out of 5 stars
    3 months ago
    Great product, that works.

    Great product, that works.

  • FP
    Faye P.
    Flag of United States
    Rated 3 out of 5 stars
    3 months ago
    Expected more

    Expected more

    BiotiQuest
    2 months ago

    Hi Faye,

    Thank you for giving BiotiQuest a try and for sharing your review. We truly value your voice in our community and want to better understand your experience.

    We saw you took the product for two consecutive months and expected more. We’d love to learn more about what you were hoping to achieve. Was there a specific health goal you were working toward, or a particular outcome you didn’t see? Understanding your expectations helps us better serve you and others on their wellness journeys.

    Our probiotic formulas are designed for sustained action, and every person’s microbiome is unique. Sometimes, the shifts are subtle at first, especially when deeper balance is needed in the gut-brain or immune systems. Other times, it’s a matter of the formula not matching the body’s current needs, and we’re here to help guide that process.

    If you’re open to sharing more about your experience or goals, we’d love to help you explore which formula might be a better fit or how to get the most out of your current one.

    You can simply reply to this email or reach us at info@biotiquest.com. Either way, thank you again for trying BiotiQuest and being part of this community. We’re honored to walk this path of health and discovery with you.

    Warm regards,
    Jack
    BiotiQuest Probiotics

Get more than you ever imagined.

Sugar Shift® converts excess sugars into mannitol, which is eliminated. Breaking down these sugars, along with toxic chemicals like glyphosate, helps re-establish harmony in the gut and speed up your sugar metabolism so you can feel your best.

Gut Health

Glucose
Metabolism

Sugar Shift® produces a bunch of fancy
molecules like glutathione and mannitol,
which can help stabilize your blood sugar,
which can help kick the afternoon slump,
decrease sugar cravings, improve your
mood and more.

Mitochondrial
Health

Sugar Shift®supports the health of
your cells, which affects how your body
repairs itself. It produces melatonin and
B- Vitamins, and metabolizes copper,
all of which matters for supporting
longevity.

Gut reactions from our customers

Check out some of our blog posts about sugar metabolism and managing your health with Martha Carlin

Happy gut. Happy life.

Life-changing probiotic blends by BiotiQuest® are designed to support a balanced
gut microbiome and the collective health benefits that they can bring to your world.

After all, when the 100 trillion+ microbes in your body get off balance your
health suffers. That’s why you don’t want buy basic probiotics. You need just the
right team of bacteria to get to work and bring back harmony in your gut.

Let us help you wrangle your body’s gut microbes so you can live your best life!

Listen to Ken Kubota talk about
his experience, with Sugar Shift®.

Find out more about the
Sugar Shift® Challenge.