Star Rating

“I sleep more sound than I have in years. I never wake up groggy either. I cant wait for my next order.”

- Shelli K, Verified Customer

When the gut lining is compromised, bacterial by-products can enter the body and cause inflammation that may disrupt your sleep cycle. Our signature blend, Simple Slumber™, has been created to produce the compounds and hormones for peaceful, sound sleep. Sweet dreams!

4.4
Rated 4.4 out of 5 stars
71 Reviews

50,000+ happy customers

Simple Slumber™

Simple Slumber™

Shift your sugar metabolism and
start your journey to better health.

Simple Slumber™ helps the body produce metabolites that promote sleep and relaxation

  • Promotes peaceful, sound sleep
  • Helps support signaling between the gut & brain
  • Supports healthy nerves and blood cells
  • May reduce cellular inflammation by reducing pathogen load
  • Increases melatonin and serotonin production (the hormones that play a crucial role in regulating sleep)


Do not take if you are taking MAO or SSR inhibitors

Regular price $49.99
Regular price $39.99 Sale price $49.99
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All BiotiQuest® products are:

Gluten-free

Dairy-free

Soy-free

Non-GMO

Vegan

How Simple Slumber™ Works

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The gut microbiome is key in the connection between our digestive system and our brain. The signaling that occurs between these two systems is mediated by metabolites and other compounds produced by the gut microbiome. This signaling may result in a more relaxed and controlled sleep cycle. Simple Slumber™ helps support balanced signaling between the gut and the brain and promotes peaceful, sound sleep.

Good, sound sleep involves understanding how stress, diet and environmental factors affect the body’s metabolism and quality of sleep. Steps to improve sleep often include lifestyle changes in exercise and diet. One of the easiest ways to support a healthy sleep-wake cycle is to restore balance in your gut microbiome with probiotics formulated to target the proper signaling from the gut to the brain. Our signature blend has been created to produce compounds and hormones to promote sound, undisturbed sleep.

When the gut lining is compromised, bacterial by-products (metabolites and bacterial toxins) can cross the barrier and cause inflammation that directly affects how you sleep. You’ll find two proprietary strains in our six-strain formula carefully chosen to work in harmony with the other strains. This formula was designed to help the body produce metabolites that promote sleep and relaxation, prevent inflammatory compounds from crossing the barrier and decrease the pathogen load. Together, these six bacteria form a stable, sustainable bacterial community and help support a healthy gut microbiome and more importantly, support sound sleep.

Simple Slumber™ increases melatonin production as well as its precursor serotonin. It also activates opiate receptors for better sleep as well as the production of antioxidants such as reduced glutathione and anti-inflammatory substances such as butyrate.

Take 1 capsule daily before bed for optimal sleep and gut benefits.

Bacillus subtilis (DE111® by Deerland)

  • Produces bacteriocins that aid in keeping the intestines healthy and digestion normal.
  • If the digestive system works efficiently, it’s much easier to find restful sleep.
  • It also helps maintain healthy levels of antioxidants and metabolites that promote better sleep.

Bifidobacterium longum

  • Supports sleep and may reduce occasional anxiety.
  • It may also help reduce the impact of acute stress on the body.
  • By producing metabolites key to a healthy gut, it reduces oxidative stress and stimulates the sleep centers of the brain.

Lactobacillus plantarum (TBC LP-36™)

  • Genetic analysis of this strain indicates this organism produces short chain fatty acids and GABA (a calming metabolite) from glutamate.
  • It also produces melatonin and metabolizes fiber and other carbohydrates to produce anti-inflammatory substances.
  • Our strain is unique in its ability to degrade glyphosate to carbon, phosphate and water and sequesters and removes heavy metals such as aluminum.

Lactobacillus acidophilus

  • Helps reduce sleep-perturbation markers of stress and inflammation, thus, reducing circadian disruption and promoting sleep.
  • It produces the important amino acid glycine and malate that supports the central metabolism of the gut ecosystem.

Lactobacillus casei

  • Improves sleep under psychological stress, by reducing occasional anxiety and helps stabilize a healthy gut microbiome.
  • When blended with the other strains in this formula, it contributes to the production of serotonin, melatonin, and antioxidants.

Leuconostoc mesenteroides (TBC LM-37™)

  • Converts glucose and fructose into mannitol, a powerful free radical scavenger.
  • It produces a mucin-like capsule that may protect the gut lining and makes vitamin B12 which plays a role in the production of melatonin.
  • B12 keeps nerves and blood cells healthy and helps with normal, healthy sleep.

We believe in the transformative potential of Simple Slumber™ and want you to feel confident in giving it a try. That’s why we offer a satisfaction guarantee. If you’re not completely satisfied with how you feel after using our product, simply contact us within 30 days of your purchase, and we’ll refund your full purchase price.

This is our way of supporting your health journey—so you can take this important step toward better wellness with confidence.

4.4
Rated 4.4 out of 5 stars
Based on 71 reviews
Total 5 star reviews: 54 Total 4 star reviews: 4 Total 3 star reviews: 4 Total 2 star reviews: 4 Total 1 star reviews: 5
82%would recommend this product
71 reviews
  • JT
    Jeff T.
    Flag of United States
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    1 month ago
    False hopes again

    Took the pill for three weeks now just as good as sleep aid from Costco

  • LG
    Lucinda G.
    Flag of United States
    Verified Buyer
    I do not recommend this product
    Rated 2 out of 5 stars
    2 months ago
    I am not seeing any

    I am not seeing any improvement in my sleep

    BiotiQuest
    2 months ago

    Hi Lucinda,

    Thank you for giving our product a fair trial. I am sorry to hear that you haven't seen the improvements in your sleep that you were hoping for.

    Because every person's biochemistry is unique, supplements can sometimes react differently for different people. While we wish it worked for everyone, we understand that sometimes it just isn't the right fit.

    I want to make sure you aren't out of pocket for trying something new. Although this falls outside our usual window, I have extended our 30-day money-back guarantee for you and issued a full refund today.

    You should see those funds return to your account within 3-5 business days. We appreciate you giving us a shot!

    With Gratitude,
    Jack
    BiotiQuest Probiotics

  • ER
    Eric R.
    Verified Buyer
    I do not recommend this product
    Rated 1 out of 5 stars
    2 months ago
    Poor Delivery and Customer Service

    I never received the product despite numerous times of emailing Biotquest. I received emails saying it was shipped out. I even gave my address for it to be directly shipped to me and never received it. I eventually gave up. I also cancelled my subscriptions to other items I used to get from Biotquest.

    BiotiQuest
    2 months ago

    Dear Eric,

    Thank you for bringing this to my attention. I am very sorry to hear you never received your order despite your previous emails. We shipped a replacement order, but that was also returned to us.

    I have gone ahead and refunded you regarding the missing bottle, and I have also issued a free replacement

    regarding the address issue: We noticed the order was placed using Shop Pay. Occasionally, this system defaults to an older address stored in the app rather than the one you intend to use. We suggest double-checking the shipping field when using Shop Pay in the future to ensure everything arrives safely.

    Thank you for your patience while we resolved this for you.

    With Gratitude,
    Jack
    BiotiQuet Fulfillment Manager

  • P
    Parker
    Flag of United States
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    2 months ago
    Sleeping Through the Night Again

    I’ve been a long time Sugar Shift user, and was excited to try these new Simple Slumber probiotics. I am someone who frequently wakes up in the middle of the night, often times awake for 1-3 hours before I’m able to fall back asleep. Since starting Simple Slumber I have not had any long periods of being awake and most nights don’t wake at all until my alarm. I started taking them on Tuesday last week and my Oura ring sleep score immediately started improving!

    Monday: 78 (good) prior to Simple Slumber

    Tuesday: 83 (good)

    Wednesday: 83 (good)

    Thursday: 87 (optimal)

    Friday: 85 (optimal)

    Saturday: 94 (optimal)

    Sunday: 90 (optimal)

    And on top of that, I went from 3h40m of sleep debt to zero!!!

  • BA
    Bonnie A.
    Flag of United States
    Verified Buyer
    I do not recommend this product
    Rated 2 out of 5 stars
    2 months ago
    No effect noticed

    I didn't notice any effect from taking the simple slumber- which was disappointing.

    BiotiQuest
    2 months ago

    Hi Bonnie,

    Thank you so much for being part of the BiotiQuest community over the years. We’re truly sorry to hear that Simple Slumber didn’t meet your expectations — especially when you were hopeful for support. We know how disheartening that can feel.

    We’ll go ahead and issue a refund for your purchase, of course. More importantly, we want to thank you for giving this formula a try. While our probiotics are carefully formulated to support specific health goals, the truth is: each body, and each microbiome, responds differently. What works beautifully for one person may not land the same way for another, and that’s simply part of the uniqueness of our biology.

    If you ever feel like exploring other formulas or would like help finding a better fit for your needs, we’re always here to support you. Your journey matters to us, and we’re honored to continue walking alongside you — even when the path requires a little more curiosity and care.

    With gratitude,
    Jack
    BiotiQuest Probiotics

Get more than you ever imagined.

By supporting proper signaling between your gut and brain, Simple
Slumber™ can help improve the quality of your sleep.

Wake up feeling refreshed and rejuvenated in the morning
by reducing damage from oxidative stress (free radicals) and
supporting a healthy level of antioxidants in your body.

By correcting the signals
between your gut and brain, our probiotics
may help with insomnia and
improve the quality of your sleep.

Let us help you get the restful sleep
you deserve so you can wake up
feeling refreshed, energized, and
ready to take on the day.

Simple Slumber™ helps balance serotonin and melatonin levels, maintain healthy levels of antioxidants to reduce oxidative stress (may even help with occasional anxiety), support healthy nerves and blood cells and so much more.

Follow Martha Carlin’s blog to learn more about sleep and the gut microbiome